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Aloe vera (Aloe) has been recognized as a medicinal plant for thousands of years. Formal scientific investigations were initiated in the early 20th century to characterize the medicinal activities of Aloe and identify the active ingredients. A recent search of the National Library of Medicine identified 729 scientific articles under the Medical Subject Heading (MeSH Term) "Aloe vera". A broader search of the scientific literature using Google Scholar identified 2,140 articles with "Aloe vera" in the title. This scientific effort has led to increased interest and acceptance by main stream medicine. Aloe inner leaf gel has been identified as the primary source of active ingredients with Acemannan being the most notable. Scientific studies have shown aloe inner leaf gel to have wound healing, anti-inflammatory, immune balancing, blood sugar balancing, and anti-viral activities. Medical uses for which there are animal or human studies showing evidence for potential benefit from Aloe include wounds, type-2 diabetes, heart disease, vascular disease, inflammation, digestive disorders, viral infections, and antioxidant activity in oxidative stress. There are animal studies or human studies that suggest Aloe vera may play a beneficial role in the absorbance and bioavailability of vitamin C and vitamin B, immune support, and the reduction of disease markers such as elevated blood lipids, elevated blood sugar, and markers of oxidative stress including TBARS, SOD, catalase, and glutathione.

These investigations have also shown that common farming, harvesting and processing methods can adversely affect the amount and potency of active components of Aloe. It is now recognized that many early laboratory and clinical studies were conducted using suboptimal preparations of Aloe, which occasionally led to conflicting results. Surveys have shown many Aloe products on the market had little or no active Aloe ingredients. Therefore, consumers did not get the expected results leading to further confusion and misunderstanding about the true benefits of Aloe. Aloe inner leaf gel preparations are available in many forms including capsule, juice, gel, powder, cosmetics, soap, lotion, and shampoos which are used for many diet, health, wellness, alternative medicine, beauty, and skin care needs.

AceAloe+ is a new aloe based dietary supplement that has the highest and most consistent active ingredient (Acemannan) content of any Aloe product on the market. For the manufacture of AceAloe, plants are grown and harvested under organic conditions. To ensure maximum freshness and activity, leaves are processed within hours of harvest using proprietary methods that preserves the integrity of the active ingredients. AceAloe+ is specially formulated with a proprietary blend of Ayurvedic herbs and adaptogens to complement and enhance the natural activity of Aloe. AceAloe+ comes in convenient capsule form with a recommended dose of 2 capsules a day. Click here for a free copy of the AceAloe+ brochure



Tuesday, May 17, 2011

Aloe vera may help reduce binding of pathogenic bacteria in the stomach

The scientific report “Anti-adhesive effect of an acidic polysaccharide from Aloe vera L. var. (Haw) Berger on the binding of Helicobacter pylori to the MKN-45 cell line” by Xu et al., published November 11, 2010 in The Journal of Pharmacy and Pharmacology and listed in PubMed May 11, 2011.  This scientific article describes non-animal, laboratory experiments that suggest that a polysaccharide contained in the inner leaf gel of Aloe vera can help prevent the bacteria H. pylori from sticking to the walls of the stomach.
Significance of Findings:  H. pylori is a major cause of peptic ulcers. Once H. pylori enters the body it travels to the stomach where it sets up residence. H. pylori is able to remain in the gut by binding (sticking) to the stomach wall.  If H. pylori can not stick to the wall of the stomach it would simply flow out of the body and cause no harm. These findings suggest that addition of Aloe vera inner leaf gel preparations to the diet may help prevent H. pylori from sticking to the wall of stomach and thus it would flow out of the body without doing harm.  It is important to note that these are preliminary laboratory findings and need to be confirmed in animal studies and ultimately in humans but point to another potential medical benefit of Aloe vera.
About Helicobacter pylori: H. pylori is a common, harmful bacteria that can infect the stomach and is a major cause of peptic ulcers.  Infection with H. pylori also causes chronic, low level, inflammation of the stomach and has been strongly associated with stomach ulcers and stomach cancer.  Infection with H. pylori has been traditionally treated with antibiotics, but the emergence of antibiotic-resistant strains is now driving the need for alternative therapies.
About PubMed: PubMed is the electronic “card catalog” of scientific literature maintained by the National Library of Medicine. PubMed comprises more than 20 million biomedical citations from MEDLINE, life science journals, and online books. Today there are 731 scientific articles listed in PubMed that contain Aloe vera as a Medical Subject Heading (MeSH Term).

1 comment:

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