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Aloe vera (Aloe) has been recognized as a medicinal plant for thousands of years. Formal scientific investigations were initiated in the early 20th century to characterize the medicinal activities of Aloe and identify the active ingredients. A recent search of the National Library of Medicine identified 729 scientific articles under the Medical Subject Heading (MeSH Term) "Aloe vera". A broader search of the scientific literature using Google Scholar identified 2,140 articles with "Aloe vera" in the title. This scientific effort has led to increased interest and acceptance by main stream medicine. Aloe inner leaf gel has been identified as the primary source of active ingredients with Acemannan being the most notable. Scientific studies have shown aloe inner leaf gel to have wound healing, anti-inflammatory, immune balancing, blood sugar balancing, and anti-viral activities. Medical uses for which there are animal or human studies showing evidence for potential benefit from Aloe include wounds, type-2 diabetes, heart disease, vascular disease, inflammation, digestive disorders, viral infections, and antioxidant activity in oxidative stress. There are animal studies or human studies that suggest Aloe vera may play a beneficial role in the absorbance and bioavailability of vitamin C and vitamin B, immune support, and the reduction of disease markers such as elevated blood lipids, elevated blood sugar, and markers of oxidative stress including TBARS, SOD, catalase, and glutathione.

These investigations have also shown that common farming, harvesting and processing methods can adversely affect the amount and potency of active components of Aloe. It is now recognized that many early laboratory and clinical studies were conducted using suboptimal preparations of Aloe, which occasionally led to conflicting results. Surveys have shown many Aloe products on the market had little or no active Aloe ingredients. Therefore, consumers did not get the expected results leading to further confusion and misunderstanding about the true benefits of Aloe. Aloe inner leaf gel preparations are available in many forms including capsule, juice, gel, powder, cosmetics, soap, lotion, and shampoos which are used for many diet, health, wellness, alternative medicine, beauty, and skin care needs.

AceAloe+ is a new aloe based dietary supplement that has the highest and most consistent active ingredient (Acemannan) content of any Aloe product on the market. For the manufacture of AceAloe, plants are grown and harvested under organic conditions. To ensure maximum freshness and activity, leaves are processed within hours of harvest using proprietary methods that preserves the integrity of the active ingredients. AceAloe+ is specially formulated with a proprietary blend of Ayurvedic herbs and adaptogens to complement and enhance the natural activity of Aloe. AceAloe+ comes in convenient capsule form with a recommended dose of 2 capsules a day. Click here for a free copy of the AceAloe+ brochure



Thursday, June 23, 2011

Effects of Aloe vera on oxidative stress

A new scientific publication by Kaithwas et al just listed on PubMed has shown that Aloe vera gel can help prevent oxidative stress of the heart.  In this study oxidative stress was experimentally induced in rats using the well known compound Doxorubicin.  Compared to rats receiving placebo, rats receiving Aloe vera gel by mouth experienced significant protection against the cardio-toxic effects of oxidative stress  as measured by a panel of well known markers of myocardial oxidative stress including LDH, serum CPK, cardiac lipid peroxides, tissue catalase and tissue SOD.

These results are in good agreement with and support the findings of many other scientific publications that Aloe vera gel, when take orally, may be beneficial in reducing or reducing damage caused by oxidative stress. Collectively these data support the notion that Aloe vera gel as a dietary supplement may be play a role as an antioxidant and be beneficial in the management of oxidative stress.

Oxidative stress is an imbalance between the body’s natural production of reactive oxygen species and its ability to detoxify them.  Oxidative stress is throught to be the root cause or contributing factor to many diseases including atherosclerosis, diabetes, heart failure, chronic fatigue syndrome and rapid aging to name just a few.

PubMed is a publically accessible database of scientific literature operated by the National Institutes of Health through the National Center for Biotechnology Information and National Library of Medicine. 

Blogger Labels: dietary supplement,catalase,SOD,cardio-toxic,heart disease,aloe vera gel,aloe gel,aloe,antioxidant,Aloe vera,oxidative stress
Posted by Lex M. Cowsert, PhD at 2:19 PM

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